4 CONTRAINDICATIONS
What are the ingredients in sildenafil tablets? This Patient Information has been approved by the U.S. Food and Drug Administration. All brands listed are the registered trademarks of their respective owners and are not trademarks of Evaric Pharmaceuticals, Inc. Revised: 08/2019 Cialis vs Viagra - What's the difference women sildenafil between them?
Side Effects
• Sildenafil tablets can be taken with or without food. If you take sildenafil tablets after a high fat meal (such as a cheeseburger and french fries), sildenafil tablets may take a little longer to start working • Do nottake sildenafil tablets more than 1 time a day. • If you accidentally take too much sildenafil tablets, call your doctor or go to the nearest hospital emergency room right away. What are the possible side effects of sildenafil tablets? Sildenafil tablets can cause serious side effects .
5.4 Hearing Loss
Rarely reported side effects include: • sildenafil citrate tablets 50 mg an erection that will not go away (priapism). • sudden vision loss in one or both eyes. Stop taking sildenafil tablets and call your healthcare provider right away if you have sudden vision loss in one or both eyes. If you have these symptoms, stop taking sildenafil tablets and contact a doctor right away. The most common side effects of sildenafil tablets are: • headache • flushing • upset stomach • abnormal vision, such as changes in color vision (such as having a blue color tinge) and blurred vision • stuffy or runny nose • back pain • muscle pain • nausea • dizziness • rash In addition, heart attack, stroke, irregular heartbeats and death have happened rarely in men taking sildenafil tablets.
Mechanism of Action
Most, but not all, of these men had heart problems before taking sildenafil tablets. It is not known if sildenafil tablets caused these problems. These are not all the possible side effects of sildenafil tablets. • Store sildenafil tablets at room temperature between 20° to 25°C (68° to 77°F). Keep sildenafil tablets and all medicines out of the reach of children. Sildenafil is a medicine used to treat erection problems (erectile dysfunction). Sildenafil is also sometimes used to treat pulmonary hypertension (high blood pressure in the blood vessels that supply the lungs).
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 200mg | 90 + 6 Pills | 170.79€ 162.66€ | |
| Viagra Generic | 200mg | 30 + 2 Pills | 83.07€ 79.11€ | |
| Viagra Generic | 150mg | 270 + 10 Pills | 326.61€ 311.06€ | |
| Kamagra Polo | 100mg | 120 + 6 Pills | 327.15€ 311.57€ | |
| Viagra Generic | 100mg | 360 + 10 Pills | 330.21€ 314.49€ | |
| Kamagra | 100mg | 180 + 6 Pills | 436.79€ 415.99€ | |
| Viagra Generic | 100mg | 10 Pills | 28.91€ 27.53€ | |
| Kamagra | 100mg | 12 Pills | 55.64€ 52.99€ | |
| Viagra Generic | 50mg | 20 Pills | 40.52€ 38.59€ | |
| Kamagra Oral Jelly | 100mg | 10 Sachets | 54.55€ 51.95€ | |
| Viagra Generic | 25mg | 20 Pills | 37.74€ 35.94€ | |
| Viagra Generic | 200mg | 20 Pills | 61.69€ 58.75€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Kamagra Polo | 100mg | 60 + 4 Pills | 189.39€ 180.37€ | |
| Kamagra Oral Jelly | 100mg | 21 Sachets | 95.92€ 91.35€ | |
| Viagra Generic | 150mg | 180 + 10 Pills | 236.46€ 225.20€ |
If you have erection problems sildenafil works by temporarily increasing blood flow to your penis when you get sexually excited. In pulmonary hypertension it works by relaxing blood vessels in the chest.
- Sildenafil interacts with nitrate medications, causing dangerous drops in blood pressure.
- Store sildenafil in a cool, dry place away from children.
- 20mg is often recommended as a starting dose for ED treatment.
- Food, especially high-fat meals, can delay its onset of action.
- Regular use can improve erectile response over time if prescribed.
If you buy sildenafil for erectile dysfunction, it can also be known by the brand names Viagra, Aronix, Liberize and Nipatra. Sildenafil for pulmonary hypertension can also be known by the brand names Revatio and Grandipam.
Renal Dose Adjustments
General information about the safe and effective use of sildenafil tablets. Do not use sildenafil tablets for a condition for which it was not prescribed. Do not give sildenafil tablets to other people, even if they have the same symptoms that you have. This Patient Information leaflet summarizes the most important information about sildenafil tablets. You can ask your healthcare provider or pharmacist for information about sildenafil tablets that is written for health professionals. This medicine is available on prescription and you can also buy it from most pharmacies.
Frequently asked questions
Sudden Loss of Vision Physicians should advise patients to stop use of all PDE5 inhibitors, including sildenafil tablets, and seek medical attention in the event of a sudden loss of vision in one or both eyes. Physicians should also discuss with patients the increased risk of NAION among the general population in patients with a ''crowded'' optic disc, although evidence is insufficient to support screening of prospective users of PDE5 inhibitor, including sildenafil tablets, for this uncommon condition [see Warnings and Precautions (5.3)and Adverse Reactions (6.2)]. Sudden Hearing Loss Physicians should advise patients to stop taking PDE5 inhibitors, including sildenafil tablets, and seek prompt medical attention in the event of sudden decrease or loss of hearing. It is not possible to determine whether these events are related directly to the use of PDE5 inhibitors or to other factors [see Warnings and Precautions (5.4)and Adverse Reactions (6.2)]. Priapism Physicians should warn patients that prolonged erections greater than 4 hours and priapism (painful erections greater than 6 hours in duration) have been reported infrequently since market approval of sildenafil tablets.
7.4 Ritonavir and Other CYP3A4 Inhibitors
Avoid Use with other PDE5 Inhibitors Physicians should inform patients not to take sildenafil tablets with other PDE5 inhibitors including REVATIO or other pulmonary arterial hypertension (PAH) treatments containing sildenafil. The safety and efficacy of sildenafil tablets with other PDE5 inhibitors, including REVATIO, have not been studied [see Warnings and Precautions(5.7)]. Sexually Transmitted Disease The use of sildenafil tablets offers no protection against sexually transmitted diseases. Manufactured for: Camber Pharmaceuticals, Inc. Piscataway, NJ 08854.
7.5 Alcohol
Manufactured by: Evaric Pharmaceuticals Inc. 155 COMMERCE DRIVE, HAUPPAUGE, New York (NY) 11788, United States (USA). Sildenafil Tablets, USP (sil den' a fil) What is the most important information I should know about sildenafil tablets? Do not take sildenafil tablets if you take any other medicines called ''nitrates.'' Nitrates are used to treat chest pain (angina). Do not take sildenafil tablets if you take medicines called guanylate cyclase stimulators which include: • Riociguat (Adempas®) a medicine that treats pulmonary arterial hypertension and chronicthromboembolic pulmonary hypertension. It comes as standard tablets, chewable tablets, and as a liquid that you swallow.
Medicine brands for Sildenafil
Tell all your healthcare sildenafil tablets 125 providers that you take sildenafil tablets.If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took sildenafil tablets. Sildenafil tablets helps a man with erectile dysfunction get and keep an erection only when he is sexually excited (stimulated). Do not take sildenafil tablets if you: • take medicines called ''nitrates'' (such as nitroglycerin) • use street drugs called ''poppers'' such as amyl nitrate or amyl nitrite, and butyl nitrate • take any medicines called guanylate cyclase stimulators such as riociguat (Adempas) • are allergic to sildenafil, as contained in sildenafil tablets and REVATIO, or any of the ingredients in sildenafil tablets. See the end of this leaflet for a complete list of ingredients in sildenafil tablets. What should I tell my healthcare provider before taking sildenafil tablets?
7.3 Amlodipine
Before you take sildenafil tablets, tell your healthcare provider if you: • have or have had heart problems such as a heart attack, irregular heartbeat, angina, chest pain, narrowing of the aortic valve or heart failure • have had heart surgery within the last 6 months • have pulmonary hypertension • have had a stroke • have low blood pressure, or high blood pressure that is not controlled • have a deformed penis shape • have had an erection that lasted for more than 4 hours • have problems with your blood cells such as sickle cell anemia, multiple myeloma, or leukemia • have retinitis pigmentosa, a rare genetic (runs in families) eye disease • have ever had severe vision loss, including an eye problem called non-arteritic anterior ischemic optic neuropathy (NAION) • have bleeding problems • have or have had stomach ulcers • have liver problems • have kidney problems or are having kidney dialysis • have any other medical conditions Tell your healthcare provider about all the medicines you take*,including prescription and over-the-counter medicines, vitamins, and herbal supplements. Sildenafil tablets may affect the way other medicines work, and other medicines may affect the way sildenafil tablet works causing side effects. Especially tell your healthcare provider if you take any of the following: • medicines called nitrates (see 'What is the most important information I should know about sildenafil tablets?') • medicines called guanylate cyclase stimulators, such as riociguat (Adempas) • medicines called alpha blockers such as Hytrin (terazosin HCl), Flomax (tamsulosin HCl), Cardura (doxazosin mesylate), Minipress (prazosin HCl), Uroxatral (alfuzosin HCl), Jalyn (dutasteride and tamsulosin HCl), or Rapaflo (silodosin). In some patients, the use of sildenafil tablets with alpha-blockers can lead to a drop in blood pressure or to fainting. • medicines called HIV protease inhibitors, such as ritonavir (Norvir), indinavir sulfate (Crixivan), saquinavir (Fortovase or Invirase) or atazanavir sulfate (Reyataz) • some types of oral antifungal medicines, such as ketoconazole (Nizoral), and itraconozale (Sporanox) • some types of antibiotics, such as clarithromycin (Biaxin), telithromycin (Ketek), or erythromycin • other medicines that treat high blood pressure • other medicines or treatments for ED • sildenafil tablets contains sildenafil, which is the same medicine found in another drug called REVATIO.
Related treatment guides
Sildenafil tablets should not be used with REVATIO or with other PAH treatments containing sildenafil or any other PDE5 inhibitors (such as Adcirca [tadalafil]). • Take sildenafil tablets exactly as your healthcare provider tells you to take it. • Your healthcare provider will tell you how much sildenafil tablets to take and when to take it. • Your healthcare provider may change your dose if needed. • Take sildenafil tablets about 1 hour before sexual activity. It usually takes 30 to 60 minutes for sildenafil to work for erectile dysfunction.
- Sildenafil helps facilitate natural arousal, not cause an instant erection.
- It is important to hydrate well when taking sildenafil.
- The medication can interact with certain herbal supplements.
- Avoid sharing medication with others due to potential health risks.
- Regular check-ups can help monitor the effects of sildenafil on health.
You can take it up to 4 hours before you want to have sex. Taking sildenafil alone will not cause an erection. You need to be sexually excited for it to work.
| Condition | Risk Factors | Recommendations |
|---|---|---|
| Use with Nitrates | Risk of severe hypotension | Avoid concurrent use |
| Severe Heart Disease | Increased cardiac stress | Consult cardiologist before use |
| Severe Liver or Kidney Impairment | Altered drug metabolism | Dose adjustment or avoid use |
| Hypotension | Blood pressure too low | Use caution, monitor blood pressure |
| Retinitis Pigmentosa | Risk of vision changes | Consult eye specialist |
The most common side effects are headaches, feeling sick, indigestion and dizziness.
- Special populations require careful consideration before prescribing.
- In elderly patients (65+), clearance may be reduced; start with a lower dose.
- No dose adjustment is typically needed for patients with mild renal impairment.
- For moderate renal impairment (CrCl 30-80 mL/min), caution is advised.
- In severe renal impairment (CrCl <30 mL/min), a 25mg dose is often recommended.
- For hepatic impairment (Child-Pugh A and B), a 25mg starting dose is advised.
- Sildenafil is not recommended for patients with severe hepatic impairment.
- Safety and efficacy in pediatric patients for ED have not been established.
- Revatio is approved for pediatric PAH patients aged 1 year and older.
- The dose for pediatric PAH is based on body weight and must be carefully calculated.
- Use during pregnancy is only for PAH and requires a careful risk/benefit analysis.
Many people have no side effects or only mild ones. It can be dangerous to take sildenafil if you also take medicines called nitrates (often given for chest pain). The combination can cause a dangerous fall in your blood pressure.
| Key Point | Explanation | Advice |
|---|---|---|
| Take on an empty stomach | Food, especially high-fat meals, can delay onset | Take 30 min to 1 hour before activity |
| Avoid excessive alcohol | Can impair effectiveness and cause side effects | Limit intake during treatment |
| Report adverse effects | Headaches, vision changes, or priapism | Contact healthcare provider immediately |
| Do not exceed recommended dose | Risk of severe side effects | Follow medical advice |
| Store safely | Keep out of children’s reach | Proper storage is essential |