2 DOSAGE AND ADMINISTRATION
Tadalafil in the treatment of erectile dysfunction. A comparison of the efficacy and tolerability of tadalafil 10 mg and 20 mg in Japanese patients with severe erectile dysfunction. The journal of sexual medicine, 4(3), pp.745–752. This page was medically reviewed by Dr Alexandra Cristina Cowell, Writer & Clinical Content Reviewer on Sep 03, 2025. Next review due on Sep 03, 2028. When we present you with stats, data, opinion or a consensus, we’ll tell you where this came from. And we’ll only present data as clinically reliable if it’s come from a reputable source, such as a state or government-funded health body, a peer-reviewed medical journal, or a recognised analytics or data body. We couldn't find what you're looking for. Or, if you're looking for something we don't have yet, you can suggest something.
| Medication Class | Interaction Type | Effect | Notes |
|---|---|---|---|
| Nitrates | Dangerous | Severe blood pressure drop | Avoid combining with Cialis |
| Alpha-blockers | Caution | Potential for hypotension | Use at lowest effective dose |
| Antifungals (e.g., Ketoconazole) | Increased Tadalafil levels | Possible side effects | Adjust dosage if needed |
| Blood Pressure Medications | Additive effects | Lowered blood pressure | Monitoring recommended |
| CYP3A4 inhibitors | Prolonged Tadalafil action | Increased risk of side effects | Dose adjustment required |
All of our reviews are collected from real patients after their treatment has been delivered. We publish reviews collected through independent platforms including Reviews.io and Trustpilot. Why this page was updated on Sep 19, 2025 Content checked and updated as part of our 3-yearly periodic review, to ensure accuracy and currentness.
8.1 Pregnancy
Getting the best results when you take Cialis is the end goal. Always follow the instructions in the leaflet or on the pack and any specific guidance given to you by your doctor. If you’re taking Cialis as needed, remember to give it enough time to work. Results aren’t instant, so aim for no less than 30 minutes before sex — longer if possible. Avoiding mixing Cialis with nitrates, such as isosorbide mononitrate or GTN spray. Get Tadalafil (generic Cialis) prescription online, if approved. It’s easy with Walgreens Virtual Healthcare What is tadalafil?Tadalafil, generic for Cialis, is an oral medication prescribed to treat male sexual dysfunction, which may also be referred to as erectile dysfunction (ED) or impotence.
- Cialis 10mg can be taken with or without food.
- It is a popular choice among ED medications worldwide.
- The medication is digital and easily available online.
- Always check for legitimate pharmacies when purchasing.
- Understand that efficacy can vary between individuals.
- Don’t attempt to increase dosage on your own.
- Cialis is not intended for recreational use.
- Seek medical advice if you have persistent erectile issues.
It’s a medication in tablet form that is taken either as needed 30 minutes before sexual activity no more than once every 24 hours, or at lower strengths once daily without regard to timing of sexual activity. Tadalafil tablets are also used to treat benign prostatic hyperplasia (BPH) in men, as well as high blood pressure in the arteries of the lungs (pulmonary arterial hypertension, PAH) in men and women. An oral suspension is available for PAH. These medications should not be used at the same time or as a replacement for each other. Tadalafil, generic for Cialis, is an oral medication prescribed to treat male sexual dysfunction, which may also be referred to as erectile dysfunction (ED) or impotence.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 10mg | 180 + 8 Pills | 236.88€ 225.60€ | |
| Cialis Generic | 60mg | 120 + 8 Pills | 240.18€ 228.74€ | |
| Cialis Generic | 10mg | 120 + 6 Pills | 178.49€ 169.99€ | |
| Cialis Generic | 20mg | 10 Pills | 31.49€ 29.99€ | |
| Cialis Generic | 10mg | 30 + 4 Pills | 63.32€ 60.30€ | |
| Cialis Professional | 40mg | 90 + 2 Pills | 348.59€ 331.99€ | |
| Cialis Generic | 2.5mg | 60 + 4 Pills | 83.43€ 79.46€ | |
| Cialis Original | 20mg | 8 Pills | 61.70€ 58.76€ | |
| Cialis Original | 20mg | 64 + 4 Pills | 274.18€ 261.12€ | |
| Cialis Generic | 60mg | 90 + 6 Pills | 196.67€ 187.30€ | |
| Cialis Professional | 20mg | 120 + 4 Pills | 291.68€ 277.79€ | |
| Cialis Generic | 20mg | 30 + 4 Pills | 68.05€ 64.81€ | |
| Cialis Generic | 5mg | 360 + 10 Pills | 268.08€ 255.31€ | |
| Cialis Soft Tabs | 20mg | 20 + 2 Pills | 66.98€ 63.79€ | |
| Cialis Super Active | 20mg | 90 + 10 Pills | 314.14€ 299.18€ | |
| Cialis Generic | 10mg | 270 + 10 Pills | 308.71€ 294.01€ | |
| Cialis Generic | 40mg | 60 + 6 Pills | 130.98€ 124.74€ |
When combined with sexual stimulation, tadalafil increases blood flow to the penis, helping men get and keep an erection.
5.13 Counseling Patients About Sexually Transmitted Diseases
If you experience side effects these can be reduced with a lower dose. If you aren’t seeing the results you want, your dose can be increased. It also means that more men are likely to find a medication that helps their ED symptoms but also minimizes the risk of side effects. Cialis 10mg and 20mg will stay active in your system for up to 36 hours. Meaning once taken you have a 36-hour window where Cialis should make getting an erection easier.
Does Cialis 10mg Tablet delay ejaculation?
It does not mean you’ll have a prolonged erection and if you have an erection for four hours you should seek medical attention. By taking a low dose every day, Cialis daily maintains a constant level of the medication in your system, meaning you’re ready for sex at any time. This is why it’s a good idea to take Cialis daily at the same time every day so that it’s continuously active in your system. As far as Cialis daily vs on-demand, the answer depends on how you need Cialis to work for you. If you want spontaneous sex, Cialis daily is the better option. Tadalafil for erectile dysfunction is not effective without sexual stimulation. How to take tadalafil for best resultsWhen used on an as-needed basis, take tadalafil at least 30 minutes prior to sexual activity. It should not be taken more than once every 24 hours. When used daily, take only once per day and at the same time each day, regardless of when sexual activity occurs. Tadalafil can be taken with or without food.
What to avoid
These cause a drop in blood pressure, which can be dangerous and never take double doses or split doses. 2004.The efficacy and safety of tadalafil: an update. Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: A dose finding study. The Journal of Urology, 180(4), 1228-1234 Coward, Robert M., Carson, Culley C. 2008. When used on an as-needed basis, take tadalafil at least 30 minutes prior to sexual activity. How long does tadalafil take to work?Tadalafil is only effective for erectile dysfunction when combined with sexual stimulation. It starts working in approximately 30 to 60 minutes. Tadalafil is only effective for erectile dysfunction when combined with sexual stimulation.
In case of emergency/overdose
And similarly, if your daily dose of 2.5mg isn’t working as well as you’d like, it can then be increased to 5mg. If you experience side effects on Cialis, let your doctor or pharmacist know. They’ll suggest either lowering your dose or recommend an alternative ED treatment. To minimize the risk of side effects avoid grapefruit, drinking too much alcohol, and do not take more than one dose of Cialis per day. If you aren’t seeing the results you want on Cialis Daily 2.5mg, and don’t experience side effects, your prescriber may recommend upping your dose to Cialis 5mg daily.
Dosage for BPH
It should be equally as effective at treating ED as Cialis. There is no Cialis 40mg or Tadalafil 40mg available in the US. A tadalafil dosage of 40mg is used to treat pulmonary arterial hypertension, but this is under careful medical supervision. Doses higher than 20mg have a higher risk of side effects and can dangerously affect blood pressure. One such side effect, priapism, is an erection that lasts more than 4 hours and requires immediate medical attention. How long does tadalafil last?Tadalafil is long lasting and can be effective for up to 36 hours. Patients should seek emergency treatment for an erection that lasts longer than four hours. Tadalafil is long lasting and can be effective for up to 36 hours. What are the side effects of tadalafil?As with all medications, tadalafil can cause side effects, and some may be serious. Some common side effects of tadalafil for erectile dysfunction include headache, dyspepsia, muscle and back pain, and nasal congestion. Muscle and back pain typically go away on their own in 48 hours.
17.7 Sudden Loss of Vision
However, if your ED comes and goes, you don’t want to take a tadalafil daily dose or aren’t sexually active more than two days a week, on-demand Cialis may be best. It’s unlikely you will be prescribed it when you first start treatment. If you’ve tried a 10mg Cialis dosage, you haven’t seen results you hoped for and you didn’t have side effects, your clinician may consider prescribing the 20mg. You might feel the higher the dose the better, but if you get easy, strong erections on 10mg a higher dose isn’t going to beat that. It will however increase the risk of side effects.
Warnings for people with certain health conditions
Your clinician will evaluate whether the benefits outweigh the risk of side effects. If you’re prescribed 20mg and find either that you’re experiencing too many side effects or are not seeing the results you want, speak with your clinician. They may suggest another type of ED pill or an alternative treatment. As 20mg is the Cialis max dose there is no “Cialis 30mg” or beyond and you should never take more than one tablet in any 24 hour period. Known as the “standard dose,” Cialis 10mg is the initial dose of Cialis prescribed when starting treatment. Contact your healthcare provider if these side effects don’t go away or if they’re bothersome.Seek immediate medical help if you notice any severe side effects such as sudden hearing loss or impairment, an erection that lasts longer than four hours, a sudden drop in blood pressure, or a loss of vision in one or both eyes. Some serious but rare eye problems have occurred. These problems may lead to eyesight changes and sometimes eyesight loss. Loss of eyesight may be temporary or permanent.
- The environmental impact of pharmaceutical excretion is a concern.
- Trace amounts of Tadalafil can be found in wastewater.
- Its effects on aquatic life are not fully understood.
- Advanced water treatment plants can remove a significant portion.
- Proper disposal of unused medication helps minimize environmental contamination.
- The synthesis of Tadalafil is a multi-step chemical process.
- The starting material is often D-tryptophan methyl ester.
- The manufacturing process is subject to strict Good Manufacturing Practice (GMP).
- Quality control ensures each tablet contains the precise 10mg dose.
- Stability testing determines the shelf life of the product.
- Packaging is designed to protect the tablets from moisture and light.
- Batch numbers and expiration dates are printed on every package.
On rare occasions, tadalafil can cause abnormal heartbeat, stroke or heart attack. These complications are more likely to occur in individuals who had heart problems prior to taking tadalafil. Speak with your Walgreens healthcare provider regarding your full medical history to make sure tadalafil is safe for you to take. As with all medications, tadalafil can cause side effects, and some may be serious. Contact your healthcare provider if these side effects don’t go away or if they’re bothersome.
17.3 Concomitant Use with Drugs Which Lower Blood Pressure
At your consultation, make sure you give your doctor your full medical history. This will help them make the best initial decision about your erectile dysfunction treatment. Once you begin treatment, keep an eye out for any side effects buy cheap cialis online and let your prescriber know if they occur. Whilst it’s important you give your prescribed dose a few tries, it should ultimately offer you the results you want. If this isn’t the case, again, let your clinician know. Seek immediate medical help if you notice any severe side effects such as sudden hearing loss or impairment, an erection that lasts longer than four hours, a sudden drop in blood pressure, or a loss of vision in one or both eyes.
5.6 Alpha blockers and Antihypertensives
Tadalafil 10mg is the generic equivalent and will be equally as effective. As it’s the unbranded version, the tadalafil 10mg price will be slightly cheaper. The 10mg dose works for around 71% of men and has a lower risk of side effects than the 20mg dose. If you’re starting treatment with Cialis daily, you’ll normally be prescribed Cialis 2.5mg. This is the lowest daily dose available.
Who should not use tadalafil?
The unbranded, generic version is Tadalafil 2.5mg which once again is usually at a lower price point. But your physician can increase or decrease your dose based on your response to the treatment. This is to keep the risk of side effects low — your doctor will aim for the lowest dose possible to get the job done. (Which is 2.5mg for ‘daily’ use, and 10mg for ‘on-demand’ use. If your ‘on-demand’ dose doesn’t work well enough, your clinician may increase it to 20mg.