Topical Anesthetics for Delaying Ejaculation
What may be causing my premature ejaculation? How soon after I begin treatment can I expect improvement? How much improvement can I reasonably expect? Am I at risk of this problem recurring? Is there a generic alternative to the medicine you're prescribing?
Cited sources
Tramadol can't be used in combination with an SSRI. Side effects might include nausea, headache, sleepiness and dizziness. Tramadol can become habit-forming when taken long-term. Some medications used to treat erectile dysfunction also might help premature ejaculation. Side effects might include headache, sex tablet women facial flushing and indigestion.
Italian Society of Andrology and Sexual Medicine
These medications might be more effective when used in combination with an SSRI. Research suggests that several drugs might be helpful in treating premature ejaculation. This is a treatment for the sleeping disorder narcolepsy. Researchers are studying whether injecting Botox into the muscles that help cause ejaculation can treat premature ejaculation. This approach involves talking with a mental health provider about your relationships and experiences.
Fluoxetine (Prozac)
Sessions can help you reduce performance anxiety and find better ways of coping with stress. Counseling is most likely to help when it's used in combination with drug therapy. With premature ejaculation, you might feel that you lose some of the closeness shared with a sexual partner. You might feel angry, ashamed and upset, and turn away from your partner. Your partner also might be upset with the change in sexual intimacy. Are there any brochures or other printed material that I can take home with me? Your health care provider might ask very personal questions and might also want to talk to your partner. To cenforce 200 mg help your provider determine the cause of your problem and the best course of treatment, be ready to answer questions, such as: How often do you have premature ejaculation?
| Medication Name | Type | Typical Dosage | Onset Time | Duration of Effect | Common Side Effects | Approval Status | Available By Prescription | Estimated Cost (USD) |
|---|---|---|---|---|---|---|---|---|
| Dapoxetine | SSRI | 30 mg | 1-3 hours | 12-24 hours | Nausea, dizziness, headache | Approved | Yes | 2-5 |
| Paroxetine | SSRI | 20 mg/day | 1-2 hours | 24 hours | Fatigue, dry mouth | Approved | Yes | 1-4 |
| Sertraline | SSRI | 50 mg/day | 2-4 hours | 24 hours | Diarrhea, insomnia | Approved | Yes | 2-4 |
| Topical Anesthetics | Local anesthetic | Varies | Immediate | 30-60 minutes | Loss of sensation in area | Approved | Yes | 3-7 |
When did you first experience premature ejaculation?
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Levitra Professional | 20mg | 180 + 4 Pills | 502.31€ 478.39€ | |
| Kamagra | 100mg | 180 + 6 Pills | 436.79€ 415.99€ | |
| Kamagra Polo | 100 mg | 272 + 12 Pills | 622.94€ 593.28€ | |
| Viagra Generic | 25mg | 180 + 6 Pills | 154.93€ 147.55€ | |
| Kamagra 100 mg | 100 mg | 20 Pills | 86.09€ 81.99€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Cialis Generic | 2.5mg | 20 Pills | 40.73€ 38.79€ | |
| Viagra Original | 100mg | 48 + 4 Pills | 207.15€ 197.29€ | |
| Viagra Generic | 50mg | 60 + 4 Pills | 83.93€ 79.93€ | |
| Kamagra Soft Tabs | 100 mg | 12 Pills | 57.55€ 54.81€ | |
| Kamagra | 100mg | 120 + 6 Pills | 330.74€ 314.99€ | |
| Viagra Super Active | 100mg | 90 + 10 Pills | 165.61€ 157.72€ | |
| Viagra Super Active | 100mg | 180 + 20 Pills | 280.97€ 267.59€ | |
| Viagra Generic | 200mg | 120 + 8 Pills | 204.80€ 195.05€ | |
| Levitra Generic | 40mg | 10 Pills | 41.37€ 39.40€ |
Do you have premature ejaculation only with a specific partner or partners? Do you experience premature ejaculation when you masturbate? Do you have premature ejaculation every time you have sex? How much are you bothered by premature ejaculation? How much is your partner bothered by premature ejaculation? How satisfied are you with your current relationship?
- Dapoxetine is specifically designed for on-demand use in PE.
- Topical anesthetics require minimal use to avoid excessive numbness.
- SSRIs impact neurotransmitters involved in ejaculation control.
- Tramadol's side effects limit its routine use for PE.
- Non-drug approaches include psychological counseling and exercises.
- Pelvic strengthening exercises aid in delay of ejaculation.
- Partner education enhances understanding and support.
- Managing stress and anxiety can significantly improve PE.
- Some therapies combine medication with sex therapy sessions.
- Medical evaluation is essential before initiating treatment.
- Lifestyle factors like smoking can influence sexual performance.
- Patient adherence to treatment plans improves outcomes.
Are you also having trouble getting and keeping an erection (erectile dysfunction)? If so, what medications have you recently started or stopped taking? Deciding to talk with your health care provider is an important step. In the meantime, consider exploring other ways in which you and your partner can connect. Although premature ejaculation can cause strain and anxiety in a relationship, it is a treatable condition.
Further reading
They include antidepressants, pain relievers and drugs for erectile dysfunction. These medications might be prescribed for either on-demand or daily use. Also, they may be prescribed alone or with other treatments. A side effect of certain antidepressants is delayed orgasm. For this reason, selective serotonin reuptake inhibitors (SSRIs) are used to treat premature ejaculation.
Biological causes
The SSRI dapoxetine is often used as the first treatment for premature ejaculation in some countries. It's not currently available in the United States. Of the drugs approved for use in the United States, paroxetine seems to be the most effective. These medications usually take 5 to 10 days to begin working. But it might take 2 to 3 weeks of treatment to see the full effect.
Physical causes
If SSRIs don't improve the timing of your ejaculation, your health care provider might prescribe the tricyclic antidepressant clomipramine (Anafranil). Side effects of antidepressants might include nausea, perspiration, drowsiness and decreased sex drive. Tramadol (Ultram, Conzip, Qdolo) is a medication used to treat pain. It also has side effects that delay ejaculation. Tramadol might be prescribed when SSRIs haven't been effective. Premature ejaculation — Current concepts in the management: A narrative review.
Guidelines for Management of Premature Ejaculation
Premature ejaculation can cause partners to feel less connected or hurt. Talking about the problem is an important step. Relationship counseling or sex therapy also might be helpful. There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form.
Intromission time
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Relevant Resources to Consult on Treatment for Premature Ejaculation
You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Please, try again in a couple of minutes Several alternative medicine treatments have been studied, including yoga, meditation and acupuncture. However, more research is needed to determine their effectiveness. It's typical to feel embarrassed when talking about sexual problems. But you can trust that your health care provider has had similar conversations with many others. Disorders of ejaculation: An AUA/SMSNA guide. Pelvic floor muscle training improves erectile dysfunction and premature ejaculation: A systematic review. In: Diagnostic and Statistical Manual of Mental Disorders DSM-5-TR. National Institute of Diabetes and Digestive and Kidney Diseases. Khera M.
Treatment Options for Premature or Rapid Ejaculation at UCLA
How often do you ejaculate before you or your partner would wish? How long after you begin having intercourse do you typically ejaculate? Think back on your relationships and sexual encounters since you became sexually active. Have you had problems with premature ejaculation before? Write down any other medical conditions with which you've been diagnosed, including mental health conditions. Treatment of male sexual dysfunction.
What are Premature Ejaculation Pills?
After some practice, delaying ejaculation might become a habit that no longer requires the pause-squeeze technique. If the pause-squeeze technique causes pain or discomfort, you can try the stop-start technique. It involves stopping sexual stimulation just before ejaculation. Then waiting until the level of arousal has diminished and starting again. Condoms might make the penis less sensitive, which can help delay ejaculation.
When to see a doctor
Specially designed "climax control" condoms are available without a prescription. These condoms contain numbing agents such as benzocaine or lidocaine to delay ejaculation. They might also be made of thicker latex. Examples include Trojan Extended Pleasure and Durex Prolong. Creams, gels and sprays that contain a numbing agent — such as benzocaine, lidocaine or prilocaine — are sometimes used to treat premature ejaculation.
Neuromuscular electrical stimulation
They're applied to the penis 10 to 15 minutes before sex to reduce sensation and help delay ejaculation. However, a cream containing both lidocaine and prilocaine (EMLA) is available by prescription. Although topical numbing agents are effective and well tolerated, they have potential side effects. They may cause decreased feeling and sexual pleasure in both partners. These drugs aren't approved by the Food and Drug Administration to treat premature ejaculation, but some are used for this purpose. Premature ejaculation occurs when you ejaculate (cum) earlier than you or your partner would like during sex. It’s a common problem, affecting 30% to 40% of people with a penis. Causes include physical problems, chemical imbalances and emotional/psychological factors. Treatments include learning techniques to delay ejaculation, counseling and medications. Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Premature ejaculation (PE) is a type of sexual dysfunction that occurs when a person has an orgasm and ejaculates sooner than they or their partner would like. It often happens before or shortly after penetration during intercourse. Premature ejaculation can be a frustrating experience for both you and your sexual partner and make your sex lives less enjoyable. PE can be lifelong, meaning you’ve had it since your first sexual experience.
Analgesic, Opioid
Also note the names and strengths of all medications you are currently taking or have recently taken, including prescription drugs and those you buy without a prescription. Questions to ask your health care provider. Write down questions in advance to make the most of your time with your provider. The list below suggests questions to ask your health care provider about premature ejaculation. Don't hesitate to ask more questions during your appointment. It can also be acquired, which means you’ve had sex previously where PE wasn’t an issue.
How well do pills work against ejaculation too fast?
Premature ejaculation is a very common condition. And it's one that can be treated. Being ready to talk about premature ejaculation will help you get the treatment you need to put your sex life back on track. The information below should help you prepare to make the most of your appointment. When you make your appointment, ask if there are any restrictions you need to follow in the time leading up to your visit. Many healthcare providers would define premature ejaculation as ejaculating within one minute of beginning intercourse. The exact timing for premature ejaculation varies and only your healthcare provider can make a diagnosis. Most healthcare organizations consider ejaculation “premature” if it: Occurs sooner than you or your partner desires. Causes distress to one or both partners.
- Topical anesthetic creams temporarily desensitize the penis to delay ejaculation.
- SSRI medications like paroxetine are prescribed off-label for premature ejaculation.
- Dapoxetine is a short-acting SSRI specifically approved for PE treatment.
- Tramadol, an opioid, can help delay ejaculation but carries dependency risks.
- Topical sprays offer quick, localized numbing effects to control ejaculation timing.
- PDE5 inhibitors like sildenafil may improve performance in men with PE and ED.
- Behavioral therapies include the stop-start and squeeze techniques to extend duration.
- Kegel exercises strengthen pelvic muscles, potentially delaying ejaculation.
- Counseling and sex therapy can address psychological causes of PE.
- Combining medication with behavioral techniques enhances treatment effectiveness.
- Herbal supplements lack robust clinical evidence but are used by some for PE.
- Consultation with a healthcare provider is essential to tailor appropriate therapy.
Happens during all or almost all sexual activity. Has been occurring for longer than six months to one year.
- Dapoxetine is taken as needed, usually 1-3 hours before sex for rapid action.
- Topical anesthetics should be used sparingly to avoid numbness of partner.
- SSRIs may cause side effects like nausea, dizziness, or decreased libido.
- Tramadol carries potential for abuse and should only be used under medical supervision.
- Daily use of certain medications may be recommended for persistent PE.
- Psychological counseling helps address performance anxiety contributing to PE.
- Pelvic floor exercises improve control and delay ejaculation naturally.
- Partner involvement in therapy can improve treatment adherence.
- Discontinuing medication abruptly may cause withdrawal symptoms or rebound.
- For some men, combining therapy with lifestyle changes yields better results.
- Over-the-counter remedies should be approached cautiously and discussed with a doctor.
- Research continues into new pharmacological and non-pharmacological treatments.
Between 30% and 40% of people experience premature ejaculation at some point in their lives. It’s the most common type of sexual dysfunction in people with a penis, with about 1 in 5 people between the ages of 18 and 59 reporting premature ejaculation.