Michael Stewart, MRPharmS
Is your erection hard enough to penetrate?
Drug Interactions to Avoid
A generic version of dapoxetine is now available. It works in exactly the same way and is just as effective. Dr Fox supplies medicine on prescription and charges a small prescription fee based on the order value of each prescription. Prescriptions are issued by our doctors online and sent electronically to our pharmacy. If you have your own private paper prescription please post to our pharmacy (details).
Priligy 60mg duration of action
Dr Fox prices are 25%–50% lower than other UK online clinics. UK delivery only: £2.90 per consultation via Royal Mail Tracked 24 (1-3 working days with tracking). Use only UK home or work delivery address. Returns and refunds - unwanted items can be returned within 14 working days for a full refund. Studies suggest premature ejaculation (PE) affects up to 30% of men. Do you have difficulty in maintaining your erection until you ejaculate during intercourse?
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Do you ever rush intercourse to prevent loss of your erection?
Dapoxetine - A Clinically Relevant Approach to the Treatment of Premature Ejaculation
Dapoxetine tablets are licensed for men 18 to 64 years only. The starting dose is one 30mg tablet 1 to 3 hours before intercourse. The dose can be increased to one 60mg tablet, if time to ejaculation was not improved, providing the 30mg dose caused no serious side effects. Dapoxetine tablets can be taken with or without food. Tablets should be swallowed whole with a glass of water.
How much to take
Do not drink grapefruit juice in the 24 hours before taking dapoxetine. Do not take daily on a regular basis, or repeat a dose within 24 hours. Dapoxetine can, in some men, cause a reduction in blood pressure with dizziness and even blackouts. Men who feel lightheaded should sit with their head between their knees or lie down until symptoms resolve. They should take no further tablets without consulting a doctor. How upset is your partner with your PE?
- Priligy is effective in delaying ejaculation in many cases.
- It is not intended for use as a recreational drug.
- Follow your doctor’s advice on duration of treatment.
- Obtain a proper diagnosis before starting medication.
- Keep a record of your response to adjust dosing.
- Be cautious about combining with other medications.
- Wash hands before handling the tablets.
- Use the medication only as prescribed.
- Be aware of the possibility of withdrawal symptoms if stopped abruptly.
Is your PE affecting your overall relationship? Have you received any treatment for your PE previously? Dapoxetine may be available on the NHS but not in all areas of the UK. Some doctors prescribe SSRI antidepressant medication to treat PE.
Severe Reactions (Seek Immediate Medical Help)
Only about 10% of these men seek medical help. It is an under-detected and under-treated medical condition. The causes of PE are multiple, although significant physical disease is not likely to be the reason. Stress and psychological factors are more likely to play a big part. Ejaculatory time of less than 2 minutes from vaginal penetration to ejaculation Negative personal consequences related to the condition Dapoxetine works by increasing the levels of a chemical in the brain called serotonin.
Common Generic Alternatives
Increases in serotonin levels, in turn, delay ejaculation. After a single tablet, dapoxetine will reach maximum levels in 1 to 3 hours, and only 5% will still be in the circulation after 24 hours. Dapoxetine (Priligy) was originally researched as an SSRI (Selective serotonin reuptake inhibitor) antidepressant, but its short action time made it unsuitable. However, some men taking similar antidepressants complained of delayed ejaculation as a side effect, and dapoxetine was further investigated and developed as a medication for men with premature ejaculation. Dapoxetine does not work by affecting mood, but by working on the serotonin nerve pathways it slows the time to ejaculation. This is effective, but it is 'off label' prescribing as it is outside the licence for the use of those medications. Dapoxetine is recommended for many men with PE but it can be used alongside non-tablet treatments, such as masturbation prior to intercourse or focussed breathing, or distraction techniques. Reducing the sensitivity of the penis by wearing a thick condom or using anaesthetic gel available without prescription from a pharmacy may also help. A disposable patch which provides direct electrical stimulation to the perineal muscles just behind the testes helps control PE by increasing perineal muscle activity, but has not undergone extensive UK medical trials. Nerve stimulation has been used in trials in the priligy 30 mg price past with some success. For further information see NHS - Can premature ejaculation be controlled? The Patient Information Leaflet (PIL) is the leaflet included in the pack with a medicine and must be read before taking the medicine. It is written for patients and gives information about taking or using a medicine. Authored 23 April 2014 by Dr Tony Steele MB ChB Sheffield University 1983. Wood, Dr C. Pugh, Dr B. Babor Last reviewed 13 November 2025 Last updated 26 January 2026 Editorial policy NICE, 2026, Dapoxetine, accessed 13 November 2025 BNF/NICE, 2025, DAPOXETINE, accessed 13 November 2025 Lancet, 2006, Efficacy and tolerability of dapoxetine in treatment of premature ejaculation, accessed 13 November 2025 Priligy rated 4.47/5 in 183 product reviews See over 50,000 service reviews of Dr Fox Excellent product, puts you in full control. The 60 mg actually made me wonder at one point 'will I actually be able to finish. For average encounters then 30mg is sufficient, extra hot use 60mg I can last 8-15 minutes using priligy.
Buy dapoxetine (Priligy) tablets online
Increasing from a 30mg tablet to a 60mg would be inadvisable. Some men with underlying medical conditions should buy priligy price not take dapoxetine, without first consulting their doctor. These include men with any of the following: History of low blood pressure and symptoms caused by falls in blood pressure, such as dizziness and blackouts when standing up. Susceptibility to angle closure glaucoma (a rare form of glaucoma). Dr Fox online consultations check for these contraindications.
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A number of prescription medications also interact with dapoxetine. In the Dr Fox online consultation there are checks for interacting medication. Some interacting medication needs to be stopped 14 days before starting Priligy and not re-started for 7 days afterwards. Do not stop prescribed medicine without first consulting a doctor or pharmacist. Men taking Priligy should read the manufacturers patient information leaflet before starting treatment. Effective in treating the condition as described Dapoxetine - A Clinically Relevant Approach to the Treatment of Premature Ejaculation Access to Dapoxetine and What Patients Should Know Use of Dapoxetine in the Outpatient Management of Premature Ejaculation Evaluation of Efficacy Based on Clinical Study Data Time Course of Onset and Duration of the Therapeutic Effect Approaches to Selecting Dosing Regimens and Administration Schedules Price Comparison and Online Availability of Dapoxetine How to Safely Purchase Dapoxetine Online from Verified Suppliers The Role of Dapoxetine in Modern Urological and Sexological Practice Dapoxetine is a breakthrough oral medication developed specifically for the treatment of premature ejaculation (PE), and it stands apart from all earlier off-label approaches that were only partially suitable for this indication. Unlike traditional antidepressants that were simply repurposed, dapoxetine was engineered from the start with the goal of giving men rapid, predictable control over ejaculation while preserving natural sexual response. This targeted design means that the drug can be used “on demand,” just before intercourse, which fits the real-life needs of couples far better than daily antidepressant regimens. Men who previously felt that PE was an unchangeable part of their life can now rely on a focused pharmacological tool that directly addresses the neurochemical mechanisms behind rapid ejaculation.
| Side Effect | Frequency | Severity | Notes |
|---|---|---|---|
| Nausea | Common | Mild | Usually transient |
| Headache | Common | Mild | Can be treated with analgesics |
| Dizziness | Less common | Mild | Post-dose, avoid driving |
| Insomnia | Less common | Mild | Sometimes reported |
The key to the clinical relevance of dapoxetine lies in its ability to significantly prolong intravaginal ejaculatory latency time (IELT) and, just as importantly, to improve subjective control, sexual satisfaction, and reduction of distress. PE is not only a question of minutes on a stopwatch; it is a complex biopsychosocial condition that affects self-esteem, relationship stability, and emotional wellbeing.
- Priligy can be effective in improving sexual confidence.
- Combining therapy with counseling may yield better results.
- Do not take Priligy if you are allergic to dapoxetine.
- The medication is not a cure but manages symptoms of PE.
- It is only suitable for men with diagnosed premature ejaculation.
- Avoid heavy machinery or driving after taking Priligy.
- The medication should not be crushed or broken.
- Use with caution in combination with other prescribed drugs.
- Discuss possible interactions with your healthcare provider.
Dapoxetine has demonstrated robust benefits across these domains. Men frequently report a renewed sense of confidence, less performance anxiety, and the ability to focus on intimacy rather than fear of “finishing too soon.” These qualitative improvements translate into better communication with partners and a more relaxed, mutually satisfying sexual life.
- Dapoxetine in Priligy increases serotonin levels in the brain.
- The medication helps delay ejaculation by improving control.
- Priligy is available in some countries only via prescription.
- Take Priligy with water, with or without food.
- Alcohol consumption may increase the risk of side effects.
- Use cautiously if you have heart, liver, or kidney issues.
- The medication may cause dizziness, so avoid driving initially.
- Priligy is not suitable for men under 18.
- Store the tablets in a cool, dry place away from children.
A major advantage of dapoxetine is its flexible dosing strategy. Because it is taken one to three hours before anticipated sexual activity, patients can align medication use with their personal schedule. This is especially relevant for men who do not have frequent intercourse or who prefer not to be on chronic daily treatment. Clinical practice shows that many men appreciate the autonomy of choosing when to medicate and when not to, rather than being locked into a fixed routine.
General Usage Guidelines
There is a potential for an increase in side effects, some serious, in men who take dapoxetine whilst using ketamine, MDMA, ecstasy, LSD, heroin, or sedatives such as benzodiazepines or other sleeping tablets. Dapoxetine may increase the effects of alcohol and alcohol increases the risk of low blood pressure problems. As with any medication, side effects are possible. See the manufacturers patient information leaflet for details. Most side effects are not medically significant and are tolerated, but some side effects can be more serious.
How many minutes does dapoxetine make you last?
Stop taking dapoxetine and see your doctor straight away if: You faint or feel lightheaded when you stand up You notice any changes in your mood You have any thoughts of suicide or harming yourself It can lead to an avoidance of intercourse and come between men and their partners. A doctor's consultation may help to get to the bottom of associated psychological problems. A doctor might ask some of the following questions: What is the time between penetration and ejaculation ('coming')? Do you feel bothered, annoyed, and/or frustrated by your PE? Have you experienced PE since your first sexual experience and on every/almost every attempt and with every partner? This on-demand approach also facilitates dose titration: a man may start at a lower dose, assess the degree of ejaculatory control and tolerability, and then adjust upward if necessary under medical supervision to reach an optimal balance.