Understanding Sildenafil Medication and Its Uses
[9] It is unclear if it is effective for treating sexual dysfunction in females. [8] It can be taken orally (swallowed by mouth), intravenously (injection into a vein), or through the sublingual route (dissolved under the tongue).
Medical uses
For current full prescribing information, please visit Cardura (doxazosin mesylate), and Minipress (prazosin HCl) are registered trademarks of Pfizer Inc. The other brands listed are trademarks of their respective owners and are not trademarks of Pfizer Inc. The makers of these brands are not affiliated with and do not endorse Pfizer Inc or its products. All content on this page has been medically reviewed by: Hassan Thwaini, Clinical Pharmacist and Copywriter, Master of Pharmacy (MPharm) on 30 March, 2026. Sildenafil is an effective treatment for erectile dysfunction.
Platelet-aggregation Inhibitors
It contains the same active ingredient as branded alternatives. Sildenafil works by encouraging more blood to flow to the penis, ensuring a strong erection when you need one. It’s effective for 82% of men.1 Find the clinically proven ED treatment that suits you best. No names, no logos, no delivery fee. 4.6* from over 33,000 people like you. [8][10] Onset when taken orally is typically within twenty minutes and lasts for about two hours.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Kamagra Soft Tabs | 100mg | 180 + 8 Pills | 425.45€ 405.19€ | |
| Viagra Generic | 150mg | 60 + 4 Pills | 111.25€ 105.95€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Viagra Generic | 50mg | 60 + 4 Pills | 83.93€ 79.93€ | |
| Viagra Generic | 25mg | 30 + 4 Pills | 47.97€ 45.69€ | |
| Kamagra Oral Jelly | 100mg | 110 + 9 Sachets | 334.87€ 318.92€ | |
| Kamagra Soft Tabs | 100mg | 60 + 4 Pills | 180.59€ 171.99€ | |
| Viagra Generic | 100mg | 270 + 10 Pills | 270.47€ 257.59€ | |
| Kamagra Polo | 100mg | 60 + 4 Pills | 189.39€ 180.37€ | |
| Viagra Generic | 25mg | 360 + 10 Pills | 213.68€ 203.50€ | |
| Kamagra Polo | 100mg | 12 Pills | 60.21€ 57.34€ | |
| Kamagra Polo | 100mg | 32 Pills | 125.88€ 119.89€ | |
| Viagra Generic | 100mg | 20 Pills | 45.58€ 43.41€ | |
| Viagra Generic | 25mg | 270 + 8 Pills | 184.26€ 175.49€ | |
| Viagra Generic | 50mg | 90 + 6 Pills | 107.37€ 102.26€ |
Common side effects include headaches, heartburn, and flushed skin.
Warnings & Precautions
Most, but not all, of these men had heart problems before taking SILDENAFIL CITRATE TABLETS. It is not known if SILDENAFIL CITRATE TABLETS caused these problems. Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all the possible side effects of SILDENAFIL CITRATE TABLETS. For more information, ask your healthcare provider or pharmacist.
Drug Cost Over Time (2014 - 2023)
You may report side effects to FDA at 1-800-FDA-1088. How should I store SILDENAFIL CITRATE TABLETS? Store SILDENAFIL CITRATE TABLETS at room temperature between 68°F to 77°F (20°C to 25°C). Keep SILDENAFIL CITRATE TABLETS and all medicines sildenafil pink pill out of the reach of children. General information about the safe and effective use of SILDENAFIL CITRATE TABLETS. [8] Caution is advised in those with cardiovascular disease. [8] Rare but serious side effects include vision problems, hearing loss, and prolonged erection (priapism) that can lead to damage to the penis.
- Sildenafil is a medication used to treat erectile dysfunction in men.
- It works by increasing blood flow to the penis during arousal.
- Sildenafil is commonly sold under the brand name Viagra.
- The typical dose ranges from 25 mg to 100 mg, taken before sexual activity.
- It usually takes about 30 to 60 minutes to work after ingestion.
- Sildenafil's effects can last for up to 4-6 hours.
- It can cause side effects like headaches, flushing, and nasal congestion.
- Sildenafil should not be used with nitrate medications due to risk of dangerous drops in blood pressure.
- It is available by prescription from a healthcare provider.
- Do not take sildenafil more than once a day to avoid adverse effects.
[8] Sildenafil should not be taken by people on nitric oxide donors such as nitroglycerin, as this may result in a serious drop in blood pressure.
- Do not take sildenafil if you have a history of heart attack or stroke.
- Women and children should not use sildenafil products.
- The medication can cause temporary vision disturbances, including blue-tinted vision.
- Always consult a healthcare provider before starting sildenafil therapy.
- Use caution when driving or operating machinery after taking sildenafil.
- Sildenafil is contraindicated in people with hypersensitivity to the drug.
- Some users report improved erectile function within 15 minutes.
- It is essential to stay hydrated, but avoid consuming large amounts of alcohol.
- Men with certain health conditions should undergo a medical exam before use.
- Overuse or misuse of sildenafil can lead to serious health complications.
Sildenafil acts by blocking phosphodiesterase 5 (PDE5), an enzyme that promotes breakdown of cGMP, which regulates blood flow in the penis. [8] It requires sexual arousal to work, and does not by itself cause or increase sexual arousal.
When oral medications might not be safe
Take SILDENAFIL CITRATE TABLETS exactly as your healthcare provider tells you to take it. Your healthcare provider will tell you how much SILDENAFIL CITRATE TABLETS to take and when to take it. Your healthcare provider may change your dose if needed. Take SILDENAFIL CITRATE TABLETS about 1 hour before sexual activity. You may take SILDENAFIL CITRATE TABLETS between 30 minutes to 4 hours before sexual activity if needed.
Your questions answered
SILDENAFIL CITRATE TABLETS can be taken with or without food. If you take SILDENAFIL CITRATE TABLETS after a high fat meal (such as a cheeseburger and french fries), SILDENAFIL CITRATE TABLETS may take a little longer to start working Do not take SILDENAFIL CITRATE TABLETS more than 1 time a day. If you accidentally take too much SILDENAFIL CITRATE TABLETS, call your doctor or go to the nearest hospital emergency room right away. What are the possible side effects of SILDENAFIL CITRATE TABLETS? SILDENAFIL CITRATE TABLETS can cause serious side effects. [8] It also results in dilation of the blood vessels in the lungs.
What is sildenafil?
an erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, get medical help right away. If it is not treated right away, priapism can permanently damage your penis. sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION).
Serious Side Effects
It is uncertain whether PDE5 inhibitors directly cause the vision loss. Stop taking SILDENAFIL CITRATE TABLETS and call your healthcare provider right away if you have sudden vision loss in one or both eyes. Some people may also have ringing in their ears (tinnitus) or dizziness. If you have these symptoms, canadian sildenafil citrate stop taking SILDENAFIL CITRATE TABLETS and contact a doctor right away. The most common side effects of SILDENAFIL CITRATE TABLETS are: abnormal vision, such as changes in color vision (such as having a blue color tinge) and blurred vision In addition, heart attack, stroke, irregular heartbeats and death have happened rarely in men taking SILDENAFIL CITRATE TABLETS. Pfizer originally discovered the medication in 1989 while looking for a treatment for angina. [11] It was approved for medical use in the United States and in the European Union in 1998. [5][8][11][12] In 2023, it was the 151st most commonly prescribed medication in the United States, with more than 3 million prescriptions. [13][14] It is available as a generic medication. [15][16] In the United Kingdom, it is available as a pharmacy medicine. The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete sexual intercourse). Its use is now one of the standard treatments for erectile dysfunction, including for males with diabetes mellitus. Tentative evidence suggests that sildenafil may help males who experience antidepressant-induced erectile dysfunction.
| Condition | Effect | Notes |
|---|---|---|
| Pulmonary Arterial Hypertension | Vasodilation benefits | Under medical supervision |
| Raynaud’s Phenomenon | Improved blood flow | Off-label, consult specialist |
| Altitude Sickness | Potential blood flow enhancement | Less proven, caution advised |
While sildenafil improves some markers of disease in people with pulmonary arterial hypertension, it does not appear to affect the risk of death or serious side effects. Sildenafil and other PDE5 inhibitors are used off-label to alleviate vasospasm and treat severe ischemia and ulcers in fingers and toes for people with secondary Raynaud's phenomenon;[9][21] these drugs have moderate efficacy for reducing the frequency and duration of vasospastic episodes. [9] As of 2016,[update] their role more generally in Raynaud's was not clear.
Non-medical use
SILDENAFIL CITRATE TABLETS may affect the way other medicines work, and other medicines may affect the way SILDENAFIL CITRATE TABLETS works causing side effects. Especially tell your healthcare provider if you take any of the following: medicines called nitrates (see "What is the most important information I should know about SILDENAFIL CITRATE TABLETS?") medicines called guanylate cyclase stimulators, such as riociguat (Adempas) medicines called alpha blockers such as Hytrin (terazosin HCl), Flomax (tamsulosin HCl), Cardura (doxazosin mesylate), Minipress (prazosin HCl), Uroxatral (alfuzosin HCl), Jalyn (dutasteride and tamsulosin HCl), or Rapaflo (silodosin). Alpha-blockers are sometimes prescribed for prostate problems or high blood pressure. In some patients, the use of SILDENAFIL CITRATE TABLETS with alpha-blockers can lead to a drop in blood pressure or to fainting. medicines called HIV protease inhibitors, such as ritonavir (Norvir), indinavir sulfate (Crixivan), saquinavir (Fortovase or Invirase) or atazanavir sulfate (Reyataz) some types of oral antifungal medicines, such as ketoconazole (Nizoral), and itraconazole (Sporanox) some types of antibiotics, such as clarithromycin (Biaxin), telithromycin (Ketek), or erythromycin other medicines that treat high blood pressure SILDENAFIL CITRATE TABLETS contains sildenafil, which is the same medicine found in another drug called SILDENAFIL TABLETS.
Study of Dose–Response, Efficacy, and Safety
SILDENAFIL TABLETS is used to treat a rare disease called pulmonary arterial hypertension (PAH). SILDENAFIL CITRATE TABLETS should not be used with SILDENAFIL TABLETS or with other PAH treatments containing sildenafil or any other PDE5 inhibitors (such as Adcirca [tadalafil]). Ask your healthcare provider or pharmacist for a list of these medicines, if you are not sure. Keep a list of them to show to your healthcare provider and pharmacist when you get a new medicine. How should I take SILDENAFIL CITRATE TABLETS? Sildenafil has shown some potential for improving exercise performance at high altitudes. However, its overall efficacy is not clear.
- Sildenafil has been shown to aid men with diabetes-related ED.
- The drug may also reduce blood pressure temporarily.
- Some men may not respond to sildenafil due to various health factors.
- It is recommended to take sildenafil on an empty stomach for faster effects.
- Overdose symptoms include dizziness, fainting, and pain in the chest.
- Sildenafil should not be used with other erectile dysfunction medications simultaneously.
- Patients should inform their doctor if they experience prolonged erections.
- Certain medical conditions require cautious use of sildenafil.
- The medication can sometimes cause changes in color perception.
- Always check the expiration date before using sildenafil pills.
Sildenafil has been studied for high-altitude pulmonary edema (HAPE), but its use is currently not recommended for that indication.
Further information
Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Do not use SILDENAFIL CITRATE TABLETS for a condition for which it was not prescribed. Do not give SILDENAFIL CITRATE TABLETS to other people, even if they have the same symptoms that you have. This Patient Information leaflet summarizes the most important information about SILDENAFIL CITRATE TABLETS. If you would like more information, talk with your healthcare provider.
Special Populations
You can ask your healthcare provider or pharmacist for information about SILDENAFIL CITRATE TABLETS that is written for health professionals. For more information, go to or call 1-800-438-1985 What are the ingredients in SILDENAFIL CITRATE TABLETS? This Patient Information has been approved by the U.S. Food and Drug Administration. This product's label may have been updated. In clinical trials, the most common adverse effects of sildenafil use included headache, flushing, indigestion, nasal congestion, and impaired vision, including photophobia and blurred vision.
Sildenafil vs Tadalafil for Erectile Dysfunction
BSc (Hons) MBBS MRCGP AFHEA MA (Hons) AFMCP “Efficacy and Safety of Sildenafil Citrate for Treatment of Erectile Dysfunction in a Population With Associated Organic Risk Factors.” Journal of Andrology (2013). “Efficacy and liquid sildenafil citrate Safety of Sildenafil Citrate for Treatment of Erectile Dysfunction in a Population With Associated Organic Risk Factors.” Journal of Andrology (2013). Answer a few simple questions to get the treatment you need. Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4][8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon.